Laser Assisted Drug Delivery

LADD uses a fractional ablative laser to create microscopic channels in the skin, temporarily disrupting the barrier. This allows topically applied medications—such as 5-fluorouracil (5-FU), tacrolimus, or prostaglandin analogs—to penetrate deeply and act directly on the affected tissue. These agents can promote melanocyte activity, improve pigmentation, and enhance scar remodeling.

Fractional Alma Hybrid and Acclaro Ultraclear lasers are the most commonly used lasers for drug delivery in hypopigmented scar management.

• Alma Hybrid laser penetrates deeper and is ideal for thicker or more fibrotic scars.
• Acclaro Ultraclear laser offers more precise ablation with minimal thermal damage, making it ideal for delicate or facial areas.
  Your specialist laser dermatologist will determine the best option based on the scar's characteristics and your skin type.

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Several topical agents can be used following laser treatment to promote repigmentation, including:

• 5-Fluorouracil (5-FU) – stimulates melanocyte migration
• Tacrolimus – supports immune regulation and pigment restoration
• Prostaglandin analogs (Bimatoprost) – promotes melanin production
• These medications are selected based on your individual needs and the clinical characteristics of the scar.

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Treatment typically involves a series of 3 to 6 sessions, spaced about 4–6 weeks apart. Visible improvement depends on factors such as the depth and age of the scar, your skin type, and the topical agent used. As scar pigmentation concerns vary widely, treatment is always personalised and multimodal to achieve the best possible results.