Laser Assisted Drug Delivery

Laser-Assisted Drug Delivery (LADD) is an advanced dermatological technique where fractional laser energy creates microscopic channels in the skin. These channels allow medical-grade topical agents to penetrate deeper and more evenly than topical application alone, enhancing treatment efficacy while maintaining safety.

At Scars & Lasers, LADD is used to improve outcomes in complex skin conditions by combining precision laser technology with targeted medications. This approach allows us to individualise treatment plans for scars, pigmentation disorders, photodynamic therapy, and pigment loss.

LADD is used across a range of medical and dermatological indications, including:

• Scars – hypertrophic scars, keloids, surgical scars, acne scars
• Photodynamic Therapy (PDT) – for actinic keratoses and selected sun-damaged or precancerous lesions
• Pigment Loss (Hypopigmentation) – post-inflammatory hypopigmentation, selected scar-related pigment loss
• Skin Texture & Quality – improving collagen remodelling and skin barrier repair
• Adjunctive therapy – enhancing laser outcomes when conventional topical treatments are insufficient

In scar management, fractional lasers create controlled micro-channels within fibrotic tissue. This allows medications such as corticosteroids, anti-fibrotic agents, or regenerative compounds to reach deeper scar layers, helping to:

• Reduce scar thickness and stiffness
• Improve texture and pliability
• Enhance collagen remodelling
• Reduce recurrence risk in selected scars

Fractional Alma Hybrid and Acclaro Ultraclear lasers are our primary choice of lasers, for drug delivery in hypopigmented scar management.

• Alma Hybrid laser penetrates deeper and is ideal for thicker or more fibrotic scars.
• Acclaro Ultraclear laser offers more precise ablation with minimal thermal damage, making it ideal for delicate or facial areas.
  Your specialist laser dermatologist will determine the best option based on the scar's characteristics and your skin type.

Several topical agents can be used following laser treatment to promote repigmentation, including:

• 5-Fluorouracil (5-FU) – stimulates melanocyte migration
• Tacrolimus – supports immune regulation and pigment restoration
• Prostaglandin analogs (Bimatoprost) – promotes melanin production
• These medications are selected based on your individual needs and the clinical characteristics of the scar.

Treatment typically involves a series of 3 to 6 sessions, spaced about 4–6 weeks apart. Visible improvement depends on factors such as the depth and age of the scar, your skin type, and the topical agent used. As scar pigmentation concerns vary widely, treatment is always personalised and multimodal to achieve the best possible results.

When performed by trained dermatology specialists, LADD is a safe and well-established technique. At Scars & Lasers:

• Treatment depth and energy settings are carefully controlled
• Only medical-grade agents are used
• Patient suitability is assessed thoroughly before treatment

Temporary redness, swelling, or mild discomfort may occur and usually settles within days.

Downtime varies depending on the laser and medication used. Most patients experience:

• Mild to moderate redness for 2–5 days
• Possible light flaking or dryness
• Minimal interruption to daily activities

Your dermatologist will advise on expected recovery based on your treatment plan.

The number of sessions depends on the condition being treated:

• Scars: often 2–6 sessions
• PDT: usually 1–2 sessions per treatment area
• Pigment loss: multiple sessions over several months may be required

Treatment plans are individualised and reviewed regularly.

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Not all patients are suitable for LADD. Factors such as skin type, underlying medical conditions, active infections, and medication use are carefully considered. A specialist consultation is essential before treatment.

Scars & Lasers combines specialist dermatology expertise with advanced laser platforms and evidence-based protocols. Our team focuses on:

• Medical-grade, not cosmetic, laser care
• Individualised treatment planning
• Combining lasers and pharmacologic therapies for optimal outcomes