Rejuran®
At a glanceRejuran is an advanced skin-regeneration injectable designed to restore skin quality at a cellular level.

Rather than adding volume or altering facial shape, Rejuran works by supporting the skin's intrinsic repair mechanisms, helping to improve texture, elasticity, hydration and overall resilience.
At Scars & Lasers, Rejuran is positioned as part of a dermatologist-directed regenerative strategy. Its value lies not simply in injecting a product, but in assessing the underlying skin concern and determining whether Rejuran is appropriate on its own or whether it may be better integrated with selected laser, light or energy-based treatments.
Our access to a broad range of advanced technologies allows treatment plans to be individually tailored according to skin quality, ageing changes, pigmentation, redness, sun damage and other specific concerns.
For selected patients, Rejuran may therefore be used alone or incorporated into a carefully planned combination-treatment programme to support refined, gradual and long-term improvement in overall skin quality.
The Science Behind It
Rejuran® is formulated using highly purified polynucleotides (PN) — biologically active DNA fragments that support tissue repair and regeneration.
Once delivered into the dermis, these molecules:
- Stimulate fibroblast activity, enhancing collagen production
- Promote dermal repair and remodelling
- Improve skin hydration and barrier integrity
- Reduce inflammatory signalling within the skin
This results in progressive improvement in skin quality, rather than immediate volumisation.
Rejuran® functions as a bio-remodelling therapy, restoring the structural environment of the skin itself.
Expert Assessment Matters
- Boosts Skin Repair and Regeneration: Stimulates the skin's natural healing processes to repair damaged tissues, reduce inflammation, and promote a healthier, more youthful appearance.
- Enhances Collagen Production: Improves skin elasticity and firmness by encouraging the production of collagen, reducing the appearance of fine lines and wrinkles.
- Improves Skin Texture and Hydration: Smooths uneven skin texture and provides deep hydration, leaving the skin looking plumper and more radiant.
- Reduces Scars and Pigmentation: Effectively minimises acne scars, fine lines, and hyperpigmentation for a clearer and more even skin tone.
- Minimally Invasive with Natural Results: Offers a safe, non-surgical option with minimal downtime, delivering subtle yet noticeable improvements for a natural-looking glow.
Treatment at a Glance
Frequently Asked Questions
Rejuran is an injectable skin-regeneration treatment containing highly purified polynucleotides, commonly referred to as PN. These are introduced into the skin to support its natural repair and regenerative processes.
Unlike traditional dermal fillers, Rejuran is not primarily designed to add volume or alter facial contours. Its purpose is to improve the quality, resilience and overall condition of the skin.
Rejuran works by supporting the skin's own regenerative processes. Polynucleotides may help promote fibroblast activity and support collagen production, hydration, elasticity and tissue repair.
Rather than creating an immediate volumising effect, improvements generally develop gradually as the skin responds and remodels over time.
Depending on individual assessment, Rejuran may be considered for:
- Fine lines and early skin ageing
- Thin or crepey skin
- Poor skin texture
- Reduced elasticity and firmness
- Dehydrated or dull-looking skin
- Enlarged or visible pores
- Sun-damaged skin
- Fine lines around the eyes
- Crepey under-eye skin
- Fine lines around the mouth
- Ageing of the neck and décolletage
- Ageing of the hands
- Overall loss of skin quality and resilience
Not in the traditional sense.
Traditional dermal fillers are primarily used to restore volume, reshape facial contours or fill deeper folds. Rejuran is instead designed to improve the overall quality and condition of the skin.
Patients should not expect the same immediate volumising or contouring effect as they would from a conventional hyaluronic-acid dermal filler.
Rejuran is commonly described as a regenerative skin booster, although it differs from treatments that primarily deliver hyaluronic acid for hydration.
Its key active component is polynucleotide, and the treatment is intended to support gradual improvements in skin quality, texture, elasticity, hydration and resilience.
Yes. Rejuran may be particularly suitable for fine superficial lines and early ageing changes associated with declining skin quality, elasticity and hydration.
Common treatment areas include:
- Around the eyes
- Cheeks
- Forehead
- Around the mouth
- Neck
- Décolletage
- Hands
Deeper wrinkles caused by significant facial movement, volume loss or skin laxity may require different or additional treatments.
Yes. This is one of the areas where Rejuran may be particularly useful.
It may be considered for skin that has become:
- Thin
- Crepey
- Fragile
- Dry
- Poorly elastic
- Sun damaged
- Texturally irregular
Treatment may be particularly useful in delicate areas where improving skin quality is the primary objective.
Yes. Specific Rejuran formulations may be used for the delicate periocular or under-eye region.
Potential concerns include:
- Fine lines
- Crepey skin
- Reduced elasticity
- Thin under-eye skin
- Textural ageing
However, not all under-eye concerns are caused by poor skin quality. Eye bags, tear-trough hollowing, pigmentation, visible blood vessels and structural shadowing may require different treatments.
It may help selected patients where dark circles are partly related to thin, poor-quality or crepey under-eye skin.
However, dark circles can have many different causes, including:
- Pigmentation
- Visible blood vessels
- Thin skin
- Tear-trough hollowing
- Shadowing
- Eyelid bags
- Genetics
An accurate assessment is therefore important before determining whether Rejuran is suitable.
Rejuran may help improve overall skin texture and the appearance of enlarged or visible pores in selected patients.
The treatment is intended to improve the underlying quality of the skin rather than simply creating a temporary surface effect.
For more pronounced textural damage, Rejuran may be considered alongside other treatments where appropriate.
Yes. One of the important roles of Rejuran at Scars & Lasers is its potential integration into a broader dermatologist-directed treatment programme.
Depending on the patient's skin concerns, it may be combined with selected treatments such as:
- Fractional laser resurfacing
- Fraxel®
- UltraClear®
- VBeam®
- Excel V+®
- PicoWay®
- Other laser, light or energy-based technologies
The combination and timing of treatments should always be individually planned.
Rejuran and laser treatments work in different ways and may therefore complement one another.
Laser and energy-based treatments can target specific concerns such as pigmentation, redness, sun damage, texture and signs of ageing, while Rejuran is intended to support overall skin quality, hydration, elasticity and resilience.
For selected patients, combining different treatment modalities may allow a more comprehensive approach than relying on a single treatment alone.
Rejuran is generally administered through multiple small injections into or immediately beneath the skin.
Immediately after treatment, patients may experience:
- Small raised injection bumps
- Redness
- Swelling
- Tenderness
- Bruising
- Pinpoint bleeding
The small bumps usually gradually settle over the following hours to days, although some areas may take longer.
The number of treatments required depends on:
- The condition of the skin
- The treatment area
- The patient's age
- The degree of sun damage or ageing
- Whether Rejuran is being used alone or alongside other treatments
A course of treatments is commonly recommended rather than relying on a single session.
Improvement tends to develop gradually over weeks to months as changes occur in skin texture, hydration, elasticity and overall quality.
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Lasting skin quality is regenerated, not concealed. Rejuran® works with your skin’s own biology — rebuilding collagen, hydration and resilience for results that refine over time.

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